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Structural mechanisms of DREAM complex assembly and regulation
The DREAM complex represses cell cycle genes during quiescence through scaffolding MuvB proteins with E2F4/5 and the Rb tumor suppressor paralog p107 or p130. Upon cell cycle entry, MuvB dissociates from p107/p130 and recruits B-Myb and FoxM1 for up-regulating mitotic gene expression. To understand...
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| Publicado no: | Genes Dev |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4421984/ https://ncbi.nlm.nih.gov/pubmed/25917549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.257568.114 |
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