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DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly

In the absence of growth signals, cells exit the cell cycle and enter into G0 or quiescence. Alternatively, cells enter senescence in response to inappropriate growth signals such as oncogene expression. The molecular mechanisms required for cell cycle exit into quiescence or senescence are poorly u...

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Detalhes bibliográficos
Main Authors: Litovchick, Larisa, Florens, Laurence A., Swanson, Selene K., Washburn, Michael P., DeCaprio, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078706/
https://ncbi.nlm.nih.gov/pubmed/21498570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2034211
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