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DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly

In the absence of growth signals, cells exit the cell cycle and enter into G0 or quiescence. Alternatively, cells enter senescence in response to inappropriate growth signals such as oncogene expression. The molecular mechanisms required for cell cycle exit into quiescence or senescence are poorly u...

詳細記述

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書誌詳細
主要な著者: Litovchick, Larisa, Florens, Laurence A., Swanson, Selene K., Washburn, Michael P., DeCaprio, James A.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078706/
https://ncbi.nlm.nih.gov/pubmed/21498570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2034211
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