Fed-Batch Production of Saccharomyces cerevisiae L-Asparaginase II by Recombinant Pichia pastoris MUT(s) Strain

L-Asparaginase (ASNase) is used in the treatment of acute lymphoblastic leukemia, being produced and commercialized only from bacterial sources. Alternative Saccharomyces cerevisiae ASNase II coded by the ASP3 gene was biosynthesized by recombinant Pichia pastoris MUT(s) under the control of the AOX...

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Bibliografiske detaljer
Udgivet i:Front Bioeng Biotechnol
Main Authors: Rodrigues, David, Pillaca-Pullo, Omar, Torres-Obreque, Karin, Flores-Santos, Juan, Sánchez-Moguel, Ignacio, Pimenta, Marcela V., Basi, Tajindar, Converti, Attilio, Lopes, André M., Monteiro, Gisele, Fonseca, Luís P., Pessoa, Adalberto Jr.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Bioengineering and Biotechnology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375902/
https://ncbi.nlm.nih.gov/pubmed/30800657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00016
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