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Versatile modeling and optimization of fed batch processes for the production of secreted heterologous proteins with Pichia pastoris
BACKGROUND: Secretion of heterologous proteins depends both on biomass concentration and on the specific product secretion rate, which in turn is not constant at varying specific growth rates. As fed batch processes usually do not maintain a steady state throughout the feed phase, it is not trivial...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1712348/ https://ncbi.nlm.nih.gov/pubmed/17156474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-5-37 |
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