The secretome of Pichia pastoris in fed‐batch cultivations is largely independent of the carbon source but changes quantitatively over cultivation time

The quantitative changes of the secretome of recombinant Pichia pastoris (Komagataella phaffii) CBS7435 over the time‐course of methanol‐ or glucose‐limited fed‐batch cultures were investigated by LC‐ESI‐MS/MS to define the carbon source‐specific secretomes under controlled bioreactor conditions. In...

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Detalhes bibliográficos
Publicado no:Microb Biotechnol
Main Authors: Burgard, Jonas, Grünwald‐Gruber, Clemens, Altmann, Friedrich, Zanghellini, Jürgen, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017826/
https://ncbi.nlm.nih.gov/pubmed/31692260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1751-7915.13499
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