Fed-Batch Production of Saccharomyces cerevisiae L-Asparaginase II by Recombinant Pichia pastoris MUT(s) Strain

L-Asparaginase (ASNase) is used in the treatment of acute lymphoblastic leukemia, being produced and commercialized only from bacterial sources. Alternative Saccharomyces cerevisiae ASNase II coded by the ASP3 gene was biosynthesized by recombinant Pichia pastoris MUT(s) under the control of the AOX...

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Bibliografische gegevens
Gepubliceerd in:Front Bioeng Biotechnol
Hoofdauteurs: Rodrigues, David, Pillaca-Pullo, Omar, Torres-Obreque, Karin, Flores-Santos, Juan, Sánchez-Moguel, Ignacio, Pimenta, Marcela V., Basi, Tajindar, Converti, Attilio, Lopes, André M., Monteiro, Gisele, Fonseca, Luís P., Pessoa, Adalberto Jr.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Bioengineering and Biotechnology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375902/
https://ncbi.nlm.nih.gov/pubmed/30800657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00016
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