Fed-Batch Production of Saccharomyces cerevisiae L-Asparaginase II by Recombinant Pichia pastoris MUT(s) Strain

L-Asparaginase (ASNase) is used in the treatment of acute lymphoblastic leukemia, being produced and commercialized only from bacterial sources. Alternative Saccharomyces cerevisiae ASNase II coded by the ASP3 gene was biosynthesized by recombinant Pichia pastoris MUT(s) under the control of the AOX...

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Dettagli Bibliografici
Pubblicato in:Front Bioeng Biotechnol
Autori principali: Rodrigues, David, Pillaca-Pullo, Omar, Torres-Obreque, Karin, Flores-Santos, Juan, Sánchez-Moguel, Ignacio, Pimenta, Marcela V., Basi, Tajindar, Converti, Attilio, Lopes, André M., Monteiro, Gisele, Fonseca, Luís P., Pessoa, Adalberto Jr.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Bioengineering and Biotechnology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375902/
https://ncbi.nlm.nih.gov/pubmed/30800657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00016
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