Fed-Batch Production of Saccharomyces cerevisiae L-Asparaginase II by Recombinant Pichia pastoris MUT(s) Strain

L-Asparaginase (ASNase) is used in the treatment of acute lymphoblastic leukemia, being produced and commercialized only from bacterial sources. Alternative Saccharomyces cerevisiae ASNase II coded by the ASP3 gene was biosynthesized by recombinant Pichia pastoris MUT(s) under the control of the AOX...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Rodrigues, David, Pillaca-Pullo, Omar, Torres-Obreque, Karin, Flores-Santos, Juan, Sánchez-Moguel, Ignacio, Pimenta, Marcela V., Basi, Tajindar, Converti, Attilio, Lopes, André M., Monteiro, Gisele, Fonseca, Luís P., Pessoa, Adalberto Jr.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375902/
https://ncbi.nlm.nih.gov/pubmed/30800657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00016
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