RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation

Receptor-interacting protein kinase (RIPK) 1 functions as a key mediator of tissue homeostasis via formation of Caspase-8 activating ripoptosome complexes, positively and negatively regulating apoptosis, necroptosis, and inflammation. Here, we report an unanticipated cell-death- and inflammation-ind...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Cell
Hauptverfasser: Liccardi, Gianmaria, Ramos Garcia, Laura, Tenev, Tencho, Annibaldi, Alessandro, Legrand, Arnaud J., Robertson, David, Feltham, Rebecca, Anderton, Holly, Darding, Maurice, Peltzer, Nieves, Dannappel, Marius, Schünke, Hannah, Fava, Luca L., Haschka, Manuel D., Glatter, Timo, Nesvizhskii, Alexey, Schmidt, Alexander, Harris, Philip A., Bertin, John, Gough, Peter J., Villunger, Andreas, Silke, John, Pasparakis, Manolis, Bianchi, Katiuscia, Meier, Pascal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2019
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375735/
https://ncbi.nlm.nih.gov/pubmed/30598363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.11.010
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge