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Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2
Tumor necrosis factor (TNF) can drive inflammation, cell survival, and death. While ubiquitylation-, phosphorylation-, and nuclear factor κB (NF-κB)-dependent checkpoints suppress the cytotoxic potential of TNF, it remains unclear whether ubiquitylation can directly repress TNF-induced death. Here,...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cell Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823975/ https://ncbi.nlm.nih.gov/pubmed/29452637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.027 |
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