Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2

Tumor necrosis factor (TNF) can drive inflammation, cell survival, and death. While ubiquitylation-, phosphorylation-, and nuclear factor κB (NF-κB)-dependent checkpoints suppress the cytotoxic potential of TNF, it remains unclear whether ubiquitylation can directly repress TNF-induced death. Here,...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Annibaldi, Alessandro, Wicky John, Sidonie, Vanden Berghe, Tom, Swatek, Kirby N., Ruan, Jianbin, Liccardi, Gianmaria, Bianchi, Katiuscia, Elliott, Paul R., Choi, Sze Men, Van Coillie, Samya, Bertin, John, Wu, Hao, Komander, David, Vandenabeele, Peter, Silke, John, Meier, Pascal
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823975/
https://ncbi.nlm.nih.gov/pubmed/29452637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.027
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