RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation

Receptor-interacting protein kinase (RIPK) 1 functions as a key mediator of tissue homeostasis via formation of Caspase-8 activating ripoptosome complexes, positively and negatively regulating apoptosis, necroptosis, and inflammation. Here, we report an unanticipated cell-death- and inflammation-ind...

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Publicado no:Mol Cell
Main Authors: Liccardi, Gianmaria, Ramos Garcia, Laura, Tenev, Tencho, Annibaldi, Alessandro, Legrand, Arnaud J., Robertson, David, Feltham, Rebecca, Anderton, Holly, Darding, Maurice, Peltzer, Nieves, Dannappel, Marius, Schünke, Hannah, Fava, Luca L., Haschka, Manuel D., Glatter, Timo, Nesvizhskii, Alexey, Schmidt, Alexander, Harris, Philip A., Bertin, John, Gough, Peter J., Villunger, Andreas, Silke, John, Pasparakis, Manolis, Bianchi, Katiuscia, Meier, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375735/
https://ncbi.nlm.nih.gov/pubmed/30598363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.11.010
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