Highly Efficient Transgenesis in Ferrets Using CRISPR/Cas9-Mediated Homology-Independent Insertion at the ROSA26 Locus

The domestic ferret (Mustela putorius furo) has proven to be a useful species for modeling human genetic and infectious diseases of the lung and brain. However, biomedical research in ferrets has been hindered by the lack of rapid and cost-effective methods for genome engineering. Here, we utilized...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Yu, Miao, Sun, Xingshen, Tyler, Scott R., Liang, Bo, Swatek, Anthony M., Lynch, Thomas J., He, Nan, Yuan, Feng, Feng, Zehua, Rotti, Pavana G., Choi, Soon H., Shahin, Weam, Liu, Xiaoming, Yan, Ziying, Engelhardt, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374392/
https://ncbi.nlm.nih.gov/pubmed/30760763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37192-4
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi