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Human Bocavirus Type-1 Capsid Facilitates the Transduction of Ferret Airways by Adeno-Associated Virus Genomes

Human bocavirus type-1 (HBoV1) has a high tropism for the apical membrane of human airway epithelia. The packaging of a recombinant adeno-associated virus 2 (rAAV2) genome into HBoV1 capsid produces a chimeric vector (rAAV2/HBoV1) that also efficiently transduces human airway epithelia. As such, thi...

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Bibliographic Details
Published in:Hum Gene Ther
Main Authors: Yan, Ziying, Feng, Zehua, Sun, Xingshen, Zhang, Yulong, Zou, Wei, Wang, Zekun, Jensen-Cody, Chandler, Liang, Bo, Park, Soo-Yeun, Qiu, Jianming, Engelhardt, John F.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567599/
https://ncbi.nlm.nih.gov/pubmed/28490200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.060
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