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Establishment of a High-Yield Recombinant Adeno-Associated Virus/Human Bocavirus Vector Production System Independent of Bocavirus Nonstructural Proteins

The genome of recombinant adeno-associated virus 2 (rAAV2) remains a promising candidate for gene therapy for cystic fibrosis (CF) lung disease, but due to limitations in the packaging capacity and the tropism of this virus with respect to the airways, strategies have evolved for packaging an rAAV2...

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Bibliografski detalji
Izdano u:Hum Gene Ther
Glavni autori: Yan, Ziying, Zou, Wei, Feng, Zehua, Shen, Weiran, Park, Soo Yeun, Deng, Xuefeng, Qiu, Jianming, Engelhardt, John F.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc., publishers 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534084/
https://ncbi.nlm.nih.gov/pubmed/30398383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.173
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