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Establishment of a High-Yield Recombinant Adeno-Associated Virus/Human Bocavirus Vector Production System Independent of Bocavirus Nonstructural Proteins

The genome of recombinant adeno-associated virus 2 (rAAV2) remains a promising candidate for gene therapy for cystic fibrosis (CF) lung disease, but due to limitations in the packaging capacity and the tropism of this virus with respect to the airways, strategies have evolved for packaging an rAAV2...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Yan, Ziying, Zou, Wei, Feng, Zehua, Shen, Weiran, Park, Soo Yeun, Deng, Xuefeng, Qiu, Jianming, Engelhardt, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534084/
https://ncbi.nlm.nih.gov/pubmed/30398383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.173
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