Establishment of a High-Yield Recombinant Adeno-Associated Virus/Human Bocavirus Vector Production System Independent of Bocavirus Nonstructural Proteins

The genome of recombinant adeno-associated virus 2 (rAAV2) remains a promising candidate for gene therapy for cystic fibrosis (CF) lung disease, but due to limitations in the packaging capacity and the tropism of this virus with respect to the airways, strategies have evolved for packaging an rAAV2...

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Vydáno v:Hum Gene Ther
Hlavní autoři: Yan, Ziying, Zou, Wei, Feng, Zehua, Shen, Weiran, Park, Soo Yeun, Deng, Xuefeng, Qiu, Jianming, Engelhardt, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534084/
https://ncbi.nlm.nih.gov/pubmed/30398383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.173
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