Postentry Processing of Recombinant Adeno-Associated Virus Type 1 and Transduction of the Ferret Lung Are Altered by a Factor in Airway Secretions

We recently created a cystic fibrosis ferret model that acquires neonatal lung infection. To develop lung gene therapies for this model, we evaluated recombinant adeno-associated virus (rAAV)-mediated gene transfer to the neonatal ferret lung. Unlike in vitro ferret airway epithelial (FAE) cells, in...

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Detalhes bibliográficos
Main Authors: Yan, Ziying, Sun, Xingshen, Evans, Idil A., Tyler, Scott R., Song, Yi, Liu, Xiaoming, Sui, Hongshu, Engelhardt, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3768237/
https://ncbi.nlm.nih.gov/pubmed/23948055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2013.137
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