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Species-Specific Differences in Mouse and Human Airway Epithelial Biology of Recombinant Adeno-Associated Virus Transduction

Differences in airway epithelial biology between mice and humans have presented challenges to evaluating gene therapies for cystic fibrosis (CF) using murine models. In this context, recombinant adeno-associated virus (rAAV) type 2 and rAAV5 vectors have very different transduction efficiencies in h...

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Bibliografische gegevens
Hoofdauteurs: Liu, Xiaoming, Yan, Ziying, Luo, Meihui, Engelhardt, John F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752084/
https://ncbi.nlm.nih.gov/pubmed/16195538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0189OC
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