A Collection of Single-Domain Antibodies that Crowd Ricin Toxin’s Active Site

In this report, we used hydrogen exchange-mass spectrometry (HX-MS) to identify the epitopes recognized by 21 single-domain camelid antibodies (V(H)Hs) directed against the ribosome-inactivating subunit (RTA) of ricin toxin, a biothreat agent of concern to military and public health authorities. The...

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Detalles Bibliográficos
Publicado en:Antibodies (Basel)
Main Authors: Angalakurthi, Siva Krishna, Vance, David J., Rong, Yinghui, Nguyen, Chi My Thi, Rudolph, Michael J., Volkin, David, Middaugh, C. Russell, Weis, David D., Mantis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374049/
https://ncbi.nlm.nih.gov/pubmed/30775035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib7040045
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