ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining “stemness”

Endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) signaling have been shown to be dysregulated in multiple cancer types. Glucose regulatory protein 78 (GRP78), the master regulator of the UPR, plays a role in proliferation, invasion, and metastasis in cancer. Cancer stem cell...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Dauer, Patricia, Sharma, Nikita S., Gupta, Vineet K., Durden, Brittany, Hadad, Roey, Banerjee, Santanu, Dudeja, Vikas, Saluja, Ashok, Banerjee, Sulagna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372649/
https://ncbi.nlm.nih.gov/pubmed/30755605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1408-5
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