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GRP78‐mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells

Chemoresistance is a major therapeutic challenge that plays a role in the poor statistical outcomes in pancreatic cancer. Unfolded protein response (UPR) is one of the homeostasis mechanisms in cancer cells that have been correlated with chemoresistance in a number of cancers including pancreatic ca...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Dauer, Patricia, Sharma, Nikita S., Gupta, Vineet K., Nomura, Alice, Dudeja, Vikas, Saluja, Ashok, Banerjee, Sulagna
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120253/
https://ncbi.nlm.nih.gov/pubmed/29738634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12322
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