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Global Implications of Local Unfolding Phenomena, Probed by Cysteine Reactivity in Human Frataxin
Local events that affect specific regions of proteins are of utmost relevance for stability and function. The aim of this study is to quantitatively assess the importance of locally-focused dynamics by means of a simple chemical modification procedure. Taking human Frataxin as a working model, we in...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6370780/ https://ncbi.nlm.nih.gov/pubmed/30742023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39429-2 |
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