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Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor
S-adenosylmethionine (SAM) is an essential metabolite that acts as a cofactor for most methylation events in the cell. The N(6)-methyladenosine (m(6)A) methyltransferase METTL16 controls SAM homeostasis by regulating the abundance of SAM synthetase MAT2A mRNA in response to changing intracellular SA...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6367934/ https://ncbi.nlm.nih.gov/pubmed/30197297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.07.025 |
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