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Manipulation by methylation: garnishing mRNAs with m(6)Am

In two recent publications in Molecular Cell, Boulias et al. (2019) and Sendinc et al. (2019) use complementary approaches to map m(6)Am modification sites transcriptome-wide and demonstrate that m(6)Am can repress translation while increasing the stability of a subset of low-abundance transcripts.

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Doxtader, Katelyn A., Nam, Yunsun
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6860360/
https://ncbi.nlm.nih.gov/pubmed/31398320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.019
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