Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs

N(6)-methyladenosine (m(6)A) is the most abundant internal modification of mRNAs and is implicated in all aspects of post-transcriptional RNA metabolism. However, little is known about m(6)A modifications to circular (circ) RNAs. We developed a computational pipeline (AutoCirc) that together with de...

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Publicado no:Cell Rep
Main Authors: Zhou, Chan, Molinie, Benoit, Daneshvar, Kaveh, Pondick, Joshua V., Wang, Jinkai, Van Wittenberghe, Nicholas O., Xing, Yi, Giallourakis, Cosmas C., Mullen, Alan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705222/
https://ncbi.nlm.nih.gov/pubmed/28854373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.027
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