YTHDC1 mediates nuclear export of N(6)-methyladenosine methylated mRNAs

N(6)-methyladenosine (m(6)A) is the most abundant internal modification of eukaryotic messenger RNA (mRNA) and plays critical roles in RNA biology. The function of this modification is mediated by m(6)A-selective ‘reader’ proteins of the YTH family, which incorporate m(6)A-modified mRNAs into pathwa...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Roundtree, Ian A, Luo, Guan-Zheng, Zhang, Zijie, Wang, Xiao, Zhou, Tao, Cui, Yiquang, Sha, Jiahao, Huang, Xingxu, Guerrero, Laura, Xie, Phil, He, Emily, Shen, Bin, He, Chuan
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2017
Sujets:
Biochemistry and Chemical Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648532/
https://ncbi.nlm.nih.gov/pubmed/28984244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31311
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