FMRP Regulates the Nuclear Export of Adam9 and Psen1 mRNAs: Secondary Analysis of an N(6)-Methyladenosine Dataset

Fragile X mental retardation protein (FMRP) binds to and regulates the translation of amyloid-β protein precursor (App) mRNA, but the detailed mechanism remains to be determined. Differential methylation of App mRNA could underlie FMRP binding, message localization and translation efficiency. We sou...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Westmark, Cara J., Maloney, Bryan, Alisch, Reid S., Sokol, Deborah K., Lahiri, Debomoy K.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329887/
https://ncbi.nlm.nih.gov/pubmed/32612155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66394-y
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