Novel Roles of Amyloid-Beta Protein Precursor Metabolites in Fragile X Syndrome and Autism

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and is associated with up to 5% of autism cases. Several promising drugs are in preclinical testing for FXS; however, bench-to-bedside plans for the clinic are severely limited due to lack of validated biomarkers a...

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Gepubliceerd in:Mol Psychiatry
Hoofdauteurs: Westmark, Cara J., Sokol, Deborah K., Maloney, Bryan, Lahiri, Debomoy K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580495/
https://ncbi.nlm.nih.gov/pubmed/27573877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.134
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