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Impact of Acamprosate on Plasma Amyloid-β Precursor Protein in Youth: A Pilot Analysis in Fragile X Syndrome-Associated and Idiopathic Autism Spectrum Disorder Suggests a Pharmacodynamic Protein Marker
BACKGROUND: Understanding of the pathophysiology of autism spectrum disorder (ASD) remains limited. Brain overgrowth has been hypothesized to be associated with the development of ASD. A derivative of amyloid-β precursor protein (APP), secreted APPα (sAPPα), has neuroproliferative effects and has be...
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| Published in: | J Psychiatr Res |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253657/ https://ncbi.nlm.nih.gov/pubmed/25300441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpsychires.2014.07.011 |
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