Structural basis of antizyme-mediated regulation of polyamine homeostasis

Polyamines are organic polycations essential for cell growth and differentiation; their aberrant accumulation is often associated with diseases, including many types of cancer. To maintain polyamine homeostasis, the catalytic activity and protein abundance of ornithine decarboxylase (ODC), the commi...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Wu, Hsiang-Yi, Chen, Shin-Fu, Hsieh, Ju-Yi, Chou, Fang, Wang, Yu-Hsuan, Lin, Wan-Ting, Lee, Pei-Ying, Yu, Yu-Jen, Lin, Li-Ying, Lin, Te-Sheng, Lin, Chieh-Liang, Liu, Guang-Yaw, Tzeng, Shiou-Ru, Hung, Hui-Chih, Chan, Nei-Li
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568681/
https://ncbi.nlm.nih.gov/pubmed/26305948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508187112
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