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Minimal Antizyme Peptide Fully Functioning in the Binding and Inhibition of Ornithine Decarboxylase and Antizyme Inhibitor

Antizyme (AZ) is a protein with 228 amino acid residues that regulates ornithine decarboxylase (ODC) by binding to ODC and dissociating its homodimer, thus inhibiting its enzyme activity. Antizyme inhibitor (AZI) is homologous to ODC, but has a higher affinity than ODC for AZ. In this study, we quan...

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Detalhes bibliográficos
Main Authors: Hsieh, Ju-Yi, Yang, Jung-Yen, Lin, Chih-Li, Liu, Guang-Yaw, Hung, Hui-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170320/
https://ncbi.nlm.nih.gov/pubmed/21931692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024366
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