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Minimal Antizyme Peptide Fully Functioning in the Binding and Inhibition of Ornithine Decarboxylase and Antizyme Inhibitor

Antizyme (AZ) is a protein with 228 amino acid residues that regulates ornithine decarboxylase (ODC) by binding to ODC and dissociating its homodimer, thus inhibiting its enzyme activity. Antizyme inhibitor (AZI) is homologous to ODC, but has a higher affinity than ODC for AZ. In this study, we quan...

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Détails bibliographiques
Auteurs principaux: Hsieh, Ju-Yi, Yang, Jung-Yen, Lin, Chih-Li, Liu, Guang-Yaw, Hung, Hui-Chih
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170320/
https://ncbi.nlm.nih.gov/pubmed/21931692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024366
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