Critical Factors Governing the Difference in Antizyme-Binding Affinities between Human Ornithine Decarboxylase and Antizyme Inhibitor

Both ornithine decarboxylase (ODC) and its regulatory protein, antizyme inhibitor (AZI), can bind with antizyme (AZ), but the latter has a higher AZ-binding affinity. The results of this study clearly identify the critical amino acid residues governing the difference in AZ-binding affinities between...

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Bibliografiske detaljer
Main Authors: Liu, Yen-Chin, Liu, Yi-Liang, Su, Jia-Yang, Liu, Guang-Yaw, Hung, Hui-Chih
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084279/
https://ncbi.nlm.nih.gov/pubmed/21552531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019253
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