Determinants of the Differential Antizyme-Binding Affinity of Ornithine Decarboxylase

Ornithine decarboxylase (ODC) is a ubiquitous enzyme that is conserved in all species from bacteria to humans. Mammalian ODC is degraded by the proteasome in a ubiquitin-independent manner by direct binding to the antizyme (AZ). In contrast, Trypanosoma brucei ODC has a low binding affinity toward A...

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Hlavní autoři: Liu, Yen-Chin, Hsu, Den-Hua, Huang, Chi-Liang, Liu, Yi-Liang, Liu, Guang-Yaw, Hung, Hui-Chih
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207831/
https://ncbi.nlm.nih.gov/pubmed/22073206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026835
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