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Determinants of the Differential Antizyme-Binding Affinity of Ornithine Decarboxylase
Ornithine decarboxylase (ODC) is a ubiquitous enzyme that is conserved in all species from bacteria to humans. Mammalian ODC is degraded by the proteasome in a ubiquitin-independent manner by direct binding to the antizyme (AZ). In contrast, Trypanosoma brucei ODC has a low binding affinity toward A...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207831/ https://ncbi.nlm.nih.gov/pubmed/22073206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026835 |
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