METTL3 regulates WTAP protein homeostasis

The Wilms tumor 1 (WT1)-associated protein (WTAP) is upregulated in many tumors, including, acute myeloid leukemia (AML), where it plays an oncogenic role by interacting with different proteins involved in RNA processing and cell proliferation. In addition, WTAP is also a regulator of the nuclear co...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sorci, Melissa, Ianniello, Zaira, Cruciani, Sonia, Larivera, Simone, Ginistrelli, Lavinia Ceci, Capuano, Ernestina, Marchioni, Marcella, Fazi, Francesco, Fatica, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056540/
https://ncbi.nlm.nih.gov/pubmed/30038300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0843-z
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