Genetic analysis reveals AMPK is required to support tumor growth in murine Kras-dependent lung cancer models

AMPK, a conserved sensor of low cellular energy. can either repress or promote tumor growth depending on the context. However, no studies have examined AMPK function in autochthonous genetic mouse models of epithelial cancer. Here, we examine the role of AMPK in murine Kras(G12D) mediated non-small...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Metab
Main Authors: Eichner, Lillian J., Brun, Sonja N., Herzig, Sébastien, Young, Nathan P., Curtis, Stephanie D., Shackelford, David B., Shokhirev, Maxim N., Leblanc, Mathias, Vera, Liliana I., Hutchins, Amanda, Ross, Debbie S., Shaw, Reuben J., Svensson, Robert U.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365213/
https://ncbi.nlm.nih.gov/pubmed/30415923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.10.005
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker