Nuclear condensates of the Polycomb protein chromobox 2 (CBX2) assemble through phase separation

Polycomb group (PcG) proteins repress master regulators of development and differentiation through organization of chromatin structure. Mutation and dysregulation of PcG genes cause developmental defects and cancer. PcG proteins form condensates in the cell nucleus, and these condensates are the phy...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tatavosian, Roubina, Kent, Samantha, Brown, Kyle, Yao, Tingting, Duc, Huy Nguyen, Huynh, Thao Ngoc, Zhen, Chao Yu, Ma, Brian, Wang, Haobin, Ren, Xiaojun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364756/
https://ncbi.nlm.nih.gov/pubmed/30514760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006620
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