Nuclear condensates of the Polycomb protein chromobox 2 (CBX2) assemble through phase separation

Polycomb group (PcG) proteins repress master regulators of development and differentiation through organization of chromatin structure. Mutation and dysregulation of PcG genes cause developmental defects and cancer. PcG proteins form condensates in the cell nucleus, and these condensates are the phy...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Tatavosian, Roubina, Kent, Samantha, Brown, Kyle, Yao, Tingting, Duc, Huy Nguyen, Huynh, Thao Ngoc, Zhen, Chao Yu, Ma, Brian, Wang, Haobin, Ren, Xiaojun
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364756/
https://ncbi.nlm.nih.gov/pubmed/30514760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006620
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