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Phase-Separated Transcriptional Condensates Accelerate Target-Search Process Revealed by Live-Cell Single-Molecule Imaging

Compartmentalization by liquid-liquid phase separation is implicated in transcription. It remains unclear whether and how transcriptional condensates accelerate the search of transcriptional regulatory factors for their target sites. Furthermore, the molecular mechanisms by which regulatory factors...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Kent, Samantha, Brown, Kyle, Yang, Chou-hsun, Alsaihati, Njood, Tian, Christina, Wang, Haobin, Ren, Xiaojun
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593837/
https://ncbi.nlm.nih.gov/pubmed/33053359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108248
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