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MORC3 Forms Nuclear Condensates through Phase Separation
Phase separation can produce local structures with specific functionality in the cell, and in the nucleus, this can lead to chromatin reorganization. Microrchidia 3 (MORC3) is a human ATPase that has been implicated in autoimmune disorders and cancer. Here, we show that MORC3 forms phase-separated c...
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| Veröffentlicht in: | iScience |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6614601/ https://ncbi.nlm.nih.gov/pubmed/31284181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.06.030 |
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