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Cyclic dinucleotide-adjuvanted dengue virus nonstructural 1 protein induces protective antibody and T-cell responses
Endothelial dysfunction and vascular leak, pathogenic hallmarks of severe dengue disease, are directly triggered by the dengue virus (DENV) nonstructural protein 1 (NS1). Previous studies have shown that immunization with NS1, as well as passive transfer of NS1-immune serum or anti-NS1 monoclonal an...
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| Veröffentlicht in: | J Immunol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6363872/ https://ncbi.nlm.nih.gov/pubmed/30642979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801323 |
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