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Lipid-derived and Other Oxidative Modifications of Retinal Proteins in a Rat Model of Smith-Lemli-Opitz Syndrome

Oxidative modification of proteins can perturb their structure and function, often compromising cellular viability. Such modifications include lipid-derived adducts (e.g., 4-hydroxynonenal (HNE) and carboxyethylpyrrole (CEP)) as well as nitrotyrosine (NTyr). We compared the retinal proteome and leve...

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Publicado en:Exp Eye Res
Main Authors: Kapphahn, Rebecca J., Richards, Michael J., Ferrington, Deborah A., Fliesler, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361703/
https://ncbi.nlm.nih.gov/pubmed/30114413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2018.08.006
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