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Light-induced exacerbation of retinal degeneration in a rat model of Smith–Lemli–Opitz syndrome

Potentiation of retinal degeneration by intense light exposure, and its amelioration by an antioxidant, were studied in a rat model of Smith–Lemli–Opitz syndrome (SLOS), in comparison with normal (control) Sprague–Dawley rats. The SLOS model is created by treating rats with AY9944, a selective inhib...

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Detalhes bibliográficos
Main Authors: Vaughan, Dana K., Peachey, Neal S., Richards, Michael J., Buchan, Blake, Fliesler, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844790/
https://ncbi.nlm.nih.gov/pubmed/16360150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2005.08.008
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