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Lipid hydroperoxide formation in the retina: correlation with retinal degeneration and light damage in a rat model of Smith–Lemli–Opitz syndrome

The Smith–Lemli–Opitz syndrome (SLOS) is an autosomal recessive disease presenting with multiple congenital anomalies, caused by a defect in cholesterol biosynthesis that results in abnormally elevated levels of 7-dehydrocholesterol (7DHC). Progressive retinal degeneration has been demonstrated in a...

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Autori principali: Richards, Michael J., Nagel, Barbara A., Fliesler, Steven J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844950/
https://ncbi.nlm.nih.gov/pubmed/16199034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2005.08.016
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