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SHP2 regulates intramembranous ossification by modifying the TGFβ and BMP2 signaling pathway
SHP2 is a ubiquitously expressed protein tyrosine phosphatase, which is involved in many signaling pathways to regulate the skeletal development. In endochondral ossification, SHP2 is known to modify the osteogenic fate of osteochondroprogenitors and to impair the osteoblastic transdifferentiation o...
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| Publicado en: | Bone |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6360127/ https://ncbi.nlm.nih.gov/pubmed/30471432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2018.11.014 |
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