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SHP2 regulates intramembranous ossification by modifying the TGFβ and BMP2 signaling pathway

SHP2 is a ubiquitously expressed protein tyrosine phosphatase, which is involved in many signaling pathways to regulate the skeletal development. In endochondral ossification, SHP2 is known to modify the osteogenic fate of osteochondroprogenitors and to impair the osteoblastic transdifferentiation o...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Wang, Lijun, Huang, Jiahui, Moore, Douglas C., Song, Yueming, Ehrlich, Michael G., Yang, Wentian
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360127/
https://ncbi.nlm.nih.gov/pubmed/30471432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2018.11.014
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