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SHP2 regulates intramembranous ossification by modifying the TGFβ and BMP2 signaling pathway

SHP2 is a ubiquitously expressed protein tyrosine phosphatase, which is involved in many signaling pathways to regulate the skeletal development. In endochondral ossification, SHP2 is known to modify the osteogenic fate of osteochondroprogenitors and to impair the osteoblastic transdifferentiation o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bone
Prif Awduron: Wang, Lijun, Huang, Jiahui, Moore, Douglas C., Song, Yueming, Ehrlich, Michael G., Yang, Wentian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360127/
https://ncbi.nlm.nih.gov/pubmed/30471432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2018.11.014
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