SHP2 regulates intramembranous ossification by modifying the TGFβ and BMP2 signaling pathway

SHP2 is a ubiquitously expressed protein tyrosine phosphatase, which is involved in many signaling pathways to regulate the skeletal development. In endochondral ossification, SHP2 is known to modify the osteogenic fate of osteochondroprogenitors and to impair the osteoblastic transdifferentiation o...

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Vydáno v:Bone
Hlavní autoři: Wang, Lijun, Huang, Jiahui, Moore, Douglas C., Song, Yueming, Ehrlich, Michael G., Yang, Wentian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360127/
https://ncbi.nlm.nih.gov/pubmed/30471432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2018.11.014
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