SHP2 regulates intramembranous ossification by modifying the TGFβ and BMP2 signaling pathway

SHP2 is a ubiquitously expressed protein tyrosine phosphatase, which is involved in many signaling pathways to regulate the skeletal development. In endochondral ossification, SHP2 is known to modify the osteogenic fate of osteochondroprogenitors and to impair the osteoblastic transdifferentiation o...

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Bibliographic Details
Published in:Bone
Main Authors: Wang, Lijun, Huang, Jiahui, Moore, Douglas C., Song, Yueming, Ehrlich, Michael G., Yang, Wentian
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360127/
https://ncbi.nlm.nih.gov/pubmed/30471432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2018.11.014
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