Wordt geladen...
Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design
Two major pharmacological hurdles severely limit the widespread use of small peptides as therapeutics: poor proteolytic stability and membrane permeability. Importantly, low aqueous solubility also impedes the development of peptides for clinical use. Various elaborate side chain stapling chemistrie...
Bewaard in:
| Gepubliceerd in: | Chem Sci |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Royal Society of Chemistry
2018
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6357863/ https://ncbi.nlm.nih.gov/pubmed/30809370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc03275k |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|