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A left handed solution to peptide inhibition of the p53-MDM2 interaction
[Image: see text] Throwing tumors a left hook punch: The oncoprotein MDM2 negatively regulates the activity and stability of the tumor suppressor protein p53, and is an important molecular target for anticancer therapy. Mirror image phage display identifies a high-affinity D-peptide ligand of MDM2 t...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359147/ https://ncbi.nlm.nih.gov/pubmed/20449836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201000329 |
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