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An Ultrahigh Affinity D-Peptide Antagonist Of MDM2

The oncoprotein MDM2 negatively regulates the activity and stability of the p53 tumor suppressor, and is an important molecular target for anticancer therapy. Aided by mirror image phage display and native chemical ligation, we have previously discovered several proteolysis-resistant duodecimal D-pe...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhan, Changyou, Zhao, Le, Wei, Xiaoli, Wu, Xueji, Chen, Xishan, Yuan, Weirong, Lu, Wei-Yue, Pazgier, Marzena, Lu, Wuyuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426300/
https://ncbi.nlm.nih.gov/pubmed/22694121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm3005465
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